cells prokaryotic or eukaryotic cell culture process grown under controlled conditions In practice the "term cell culture" has come to refer to the cell culture from multicultural eukaryotes especially animal cells The historical development and methods of cell culture are closely intertwined with the culture and organ culture
Application of cell cultures
Mass culture of animal cell lines the manufacture of viral vaccines based and many products of biotechnology organic products produced by recombinant DNA (rand) technology in animal cell cultures include enzymes hormones synthetic immunobiologicals (monoclonal antibodies interleukins lymphokines) and anticancer agents Although many simpler proteins can be produced using rand in bacterial cultures more complex proteins are glycosylated (carbohydrate modified) now must be done in animal cells An important example of such protein complexes is a hormone erythropoietin mammalian cell cultures to grow high cost so research is underway to produce such complex proteins in insect cells or higher plants
Culture and tissue engineering
Cell culture is a fundamental component of tissue culture and tissue engineering as confirmed by the fundamental principles of growth and maintenance of cells ex vivo
Vaccine
Vaccines against polio measles mumps rubella and vermicelli are currently in cell culture Because the threat of an H5N1 pandemic research using cell culture influenza vaccines was funded by the US government new ideas into the field including recombinant DNA-based vaccines such as those with human adenovirus (common cold virus) as a carrier or the use of adjuvant
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